2021年8月31日火曜日

モデルナ↑

 

Moderna Creates Twice as Many Antibodies as Pfizer, Study Shows Tue, 31 August 2021
A study of almost 2,500 workers at a major Belgium hospital system found antibody levels among individuals who hadn’t been infected with the coronavirus before getting two doses of the Moderna vaccine averaged  2,881units per milliliter, compared with 1,108 units/mL in an equivalent group who got two jabs of the Pfizer shot.

2倍はゆうに超えるね。 

4週間空けたのもよかったのではないか、と言われている。

Moderna’s vaccine was associated with a two-fold risk reduction against breakthrough SARS-CoV-2 infections compared to Pfizer’s in a review of people in the Mayo Clinic Health System in the U.S. from January to July. 

2021 Aug 9;2021.08.06.21261707. doi: 10.1101/2021.08.06.21261707. Preprint
Comparison of two highly-effective mRNA vaccines for COVID-19 during periods of Alpha and Delta variant prevalence
Comparing rates of infection between matched individuals fully vaccinated with mRNA-1273 versus BNT162b2 across Mayo Clinic Health System sites in multiple states (Minnesota, Wisconsin, Arizona, Florida, and Iowa), mRNA-1273 conferred a two-fold risk reduction against breakthrough infection compared to BNT162b2 (IRR = 0.50, 95% CI: 0.39-0.64). In Florida, which is currently experiencing its largest COVID-19 surge to date, the risk of infection in July after full vaccination with mRNA-1273 was about 60% lower than after full vaccination with BNT162b2 (IRR: 0.39, 95% CI: 0.24-0.62).

なんだかよくわからないんだけど、要するに、2回ワクチン接種後の感染率もモデルナの方が低い、ということだろう。

 What do I need to know about the Moderna vaccine? And how does it compare with Pfizer? 


How long does the immunity last?

Moderna recently announced no change in efficacy six months after participants received their COVID-19 vaccines, with a 93 per cent protection against severe disease after six months, compared to 94 per cent reported in the clinical trial.


Pfizer has reported similar data, with protection sitting at 84 per cent after six months.

6ヶ月過ぎた後の重症予防効果はモデルナ93% ファイザー84%。 

 

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